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PET as a Translational Tool in Drug Development for Neuroscience Compounds

In central nervous system drug discovery programs, early development of new chemical entities (NCEs) requires a multidisciplinary strategy and a translational approach to obtain proof of distribution, proof of occupancy, and proof of function in specific brain circuits. Positron emission tomography...

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Detalles Bibliográficos
Autores principales: Varrone, Andrea, Bundgaard, Christoffer, Bang‐Andersen, Benny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305164/
https://www.ncbi.nlm.nih.gov/pubmed/35201613
http://dx.doi.org/10.1002/cpt.2548