How Staying Negative Is Good for the (Adult) Brain: Maintaining Chloride Homeostasis and the GABA-Shift in Neurological Disorders

Excitatory-inhibitory (E-I) imbalance has been shown to contribute to the pathogenesis of a wide range of neurodevelopmental disorders including autism spectrum disorders, epilepsy, and schizophrenia. GABA neurotransmission, the principal inhibitory signal in the mature brain, is critically coupled...

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Detalles Bibliográficos
Autores principales: Hui, Kelvin K., Chater, Thomas E., Goda, Yukiko, Tanaka, Motomasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305173/
https://www.ncbi.nlm.nih.gov/pubmed/35875665
http://dx.doi.org/10.3389/fnmol.2022.893111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305173/
https://www.ncbi.nlm.nih.gov/pubmed/35875665
http://dx.doi.org/10.3389/fnmol.2022.893111

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