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Mapping the Conformational Landscape of the Neutral Network of RNA Sequences That Connect Two Functional Distinctly Different Ribozymes

During evolution of an RNA world, the development of enzymatic function was essential. Such enzymatic function was linked to RNA sequences capable of adopting specific RNA folds that possess catalytic pockets to promote catalysis. Within this primordial RNA world, initially evolved self‐replicating...

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Detalles Bibliográficos
Autores principales: Knezic, Bozana, Keyhani‐Goldau, Sara, Schwalbe, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305247/
https://www.ncbi.nlm.nih.gov/pubmed/35112772
http://dx.doi.org/10.1002/cbic.202200022