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Altered Intrinsic Properties and Inhibitory Connectivity in Aged Parvalbumin-Expressing Dorsal Horn Neurons

The incidence of pain symptoms such as allodynia are known to increase with age. Parvalbumin expressing interneurons (PVINs) within the dorsal horn (DH) of the spinal cord play an important role in allodynia whereby their inhibitory connections prevent innocuous touch information from exciting nocic...

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Detalles Bibliográficos
Autores principales: Gradwell, Mark A., Smith, Kelly M., Dayas, Christopher V., Smith, Douglas W., Hughes, David I., Callister, Robert J., Graham, Brett A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305305/
https://www.ncbi.nlm.nih.gov/pubmed/35874431
http://dx.doi.org/10.3389/fncir.2022.834173