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Altered Intrinsic Properties and Inhibitory Connectivity in Aged Parvalbumin-Expressing Dorsal Horn Neurons
The incidence of pain symptoms such as allodynia are known to increase with age. Parvalbumin expressing interneurons (PVINs) within the dorsal horn (DH) of the spinal cord play an important role in allodynia whereby their inhibitory connections prevent innocuous touch information from exciting nocic...
Autores principales: | Gradwell, Mark A., Smith, Kelly M., Dayas, Christopher V., Smith, Douglas W., Hughes, David I., Callister, Robert J., Graham, Brett A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305305/ https://www.ncbi.nlm.nih.gov/pubmed/35874431 http://dx.doi.org/10.3389/fncir.2022.834173 |
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