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The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes

The low-density lipoprotein receptor (LDLR) mediates the hepatic uptake of circulating low-density lipoproteins (LDLs), a process that modulates the development of atherosclerotic cardiovascular disease. We recently identified RAB10, encoding a small GTPase, as a positive regulator of LDL uptake in...

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Detalles Bibliográficos
Autores principales: Khan, Taslima Gani, Ginsburg, David, Emmer, Brian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305350/
https://www.ncbi.nlm.nih.gov/pubmed/35753407
http://dx.doi.org/10.1016/j.jlr.2022.100248