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Long-term L-3-n-butylphthalide pretreatment attenuates ischemic brain injury in mice with permanent distal middle cerebral artery occlusion through the Nrf2 pathway

L-3-n-butylphthalide (NBP), which is used for treatment of mild and moderate acute ischemic stroke, exerts its effects by modulating the Nrf2 pathway. However, it has not been established whether NBP exerts its preventive effects in high-risk ischemic stroke patients through the Nrf2 pathway. We inv...

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Detalles Bibliográficos
Autores principales: Sun, Mingying, Jiang, Changchun, Hao, Xiwa, Pang, Jiangxia, Chen, Chao, Xiang, Wenping, Zhang, Jun, Zhao, Shijun, Wang, Po, Geng, Shangyong, Wang, Hanzhang, Li, Yuechun, Wang, Baojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305368/
https://www.ncbi.nlm.nih.gov/pubmed/35874077
http://dx.doi.org/10.1016/j.heliyon.2022.e09909