Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials

DsbA enzymes catalyze oxidative folding of proteins that are secreted into the periplasm of Gram‐negative bacteria, and they are indispensable for the virulence of human pathogens such as Vibrio cholerae and Escherichia coli. Therefore, targeting DsbA represents an attractive approach to control bac...

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Detalles Bibliográficos
Autores principales: Wang, Geqing, Mohanty, Biswaranjan, Williams, Martin L., Doak, Bradley C., Dhouib, Rabeb, Totsika, Makrina, McMahon, Róisín M., Sharma, Gaurav, Zheng, Dan, Bentley, Matthew R., Ka‐Yan Chin, Yanni, Horne, James, Chalmers, David K., Heras, Begoña, Scanlon, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305425/
https://www.ncbi.nlm.nih.gov/pubmed/34978144
http://dx.doi.org/10.1002/cmdc.202100673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305425/
https://www.ncbi.nlm.nih.gov/pubmed/34978144
http://dx.doi.org/10.1002/cmdc.202100673

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