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Effect of Phosphate Binders and a Dietary Iron Supplement on the Pharmacokinetics of a Single Dose of Vadadustat in Healthy Adults

Vadadustat is a hypoxia‐inducible factor prolyl‐hydroxylase inhibitor being developed for the treatment of anemia in patients with chronic kidney disease. Sequelae of chronic kidney disease include hyperphosphatemia and anemia, which are frequently treated with phosphate binders and iron supplements...

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Detalles Bibliográficos
Autores principales: Paulson, Susan K., Martinez, Jimena, Sawant, Rishikesh, Burke, Steven K., Chavan, Ajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305443/
https://www.ncbi.nlm.nih.gov/pubmed/35172045
http://dx.doi.org/10.1002/cpdd.1033