TSH receptor specific monoclonal autoantibody K1‐70(TM) targeting of the TSH receptor in subjects with Graves' disease and Graves' orbitopathy—Results from a phase I clinical trial

OBJECTIVES: In Graves' disease (GD), autoantibodies to the thyroid stimulating hormone receptor (TSHR) cause hyperthyroidism. The condition is often associated with eye signs including proptosis, oedema, and diplopia (collectively termed Graves' orbitopathy [GO]). The safety profile of K1‐...

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Detalles Bibliográficos
Autores principales: Furmaniak, Jadwiga, Sanders, Jane, Sanders, Paul, Li, Yang, Rees Smith, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305464/
https://www.ncbi.nlm.nih.gov/pubmed/35088429
http://dx.doi.org/10.1111/cen.14681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305464/
https://www.ncbi.nlm.nih.gov/pubmed/35088429
http://dx.doi.org/10.1111/cen.14681

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