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Understanding the Blood‐Brain Barrier and Beyond: Challenges and Opportunities for Novel CNS Therapeutics

This review addresses questions on how to accomplish successful central nervous system (CNS) drug delivery (i.e., having the right concentration at the right CNS site, at the right time), by understanding the rate and extent of blood‐brain barrier (BBB) transport and intra‐CNS distribution in relati...

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Detalles Bibliográficos
Autores principales: de Lange, Elizabeth C. M., Hammarlund Udenaes, Margareta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305478/
https://www.ncbi.nlm.nih.gov/pubmed/35220577
http://dx.doi.org/10.1002/cpt.2545