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Pharmacokinetic Differences of Wuji Pill Components in Normal and Chronic Visceral Hypersensitivity Irritable Bowel Syndrome Rats Attributable to Changes in Tight Junction and Transporters

The Wuji pill, also called Wuji Wan (WJW), is an effective traditional medicine for the clinical treatment of irritable bowel syndrome (IBS). It is principally composed of Rhizoma Coptidis, Fructus Evodiae Rutaecarpae, and Radix Paeoniae Alba. There have been no reports on the pharmacokinetics of WJ...

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Detalles Bibliográficos
Autores principales: Gong, Zipeng, Yang, Qing, Wang, Yajie, Weng, Xiaogang, Li, Yujie, Dong, Yu, Zhu, Xiaoxin, Chen, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305487/
https://www.ncbi.nlm.nih.gov/pubmed/35873589
http://dx.doi.org/10.3389/fphar.2022.948678