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Repurposing of Trimetazidine for amyotrophic lateral sclerosis: A study in SOD1(G93A) mice

BACKGROUND AND PURPOSE: Amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by the degeneration of upper and lower motor neurons, progressive wasting and paralysis of voluntary muscles and is currently incurable. Although considered to be a pure motor neuron disease, incre...

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Detalles Bibliográficos
Autores principales: Scaricamazza, Silvia, Salvatori, Illari, Amadio, Susanna, Nesci, Valentina, Torcinaro, Alessio, Giacovazzo, Giacomo, Primiano, Aniello, Gloriani, Michela, Candelise, Niccolò, Pieroni, Luisa, Loeffler, Jean‐Philippe, Renè, Frederique, Quessada, Cyril, Tefera, Tesfaye W., Wang, Hao, Steyn, Frederik J., Ngo, Shyuan T., Dobrowolny, Gabriella, Lepore, Elisa, Urbani, Andrea, Musarò, Antonio, Volonté, Cinzia, Ferraro, Elisabetta, Coccurello, Roberto, Valle, Cristiana, Ferri, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305494/
https://www.ncbi.nlm.nih.gov/pubmed/34783031
http://dx.doi.org/10.1111/bph.15738