Chemically Synthesized, Self‐Assembling Small Interfering RNA‐Prohead RNA Molecules Trigger Dicer‐Independent Gene Silencing

RNA interference (RNAi) mediated by small interfering RNA (siRNA) duplexes is a powerful therapeutic modality, but the translation of siRNAs from the bench into clinical application has been hampered by inefficient delivery in vivo. An innovative delivery strategy involves fusing siRNAs to a three‐w...

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Detalles Bibliográficos
Autores principales: Hill, Alyssa C., van Leeuwen, Daniël, Schlösser, Verena, Behera, Alok, Mateescu, Bogdan, Hall, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305526/
https://www.ncbi.nlm.nih.gov/pubmed/34879171
http://dx.doi.org/10.1002/chem.202103995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305526/
https://www.ncbi.nlm.nih.gov/pubmed/34879171
http://dx.doi.org/10.1002/chem.202103995

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