Pridopidine modifies disease phenotype in a SOD1 mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a lethal and incurable neurodegenerative disease due to the loss of upper and lower motor neurons, which leads to muscle weakness, atrophy, and paralysis. Sigma‐1 receptor (σ‐1R) is a ligand‐operated protein that exhibits pro‐survival and anti‐apoptotic propert...

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Detalles Bibliográficos
Autores principales: Estévez‐Silva, Héctor M., Mediavilla, Tomás, Giacobbo, Bruno Lima, Liu, Xijia, Sultan, Fahad R., Marcellino, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Clinical and Translational Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305776/
https://www.ncbi.nlm.nih.gov/pubmed/35080077
http://dx.doi.org/10.1111/ejn.15608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305776/
https://www.ncbi.nlm.nih.gov/pubmed/35080077
http://dx.doi.org/10.1111/ejn.15608

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