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Pridopidine modifies disease phenotype in a SOD1 mouse model of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a lethal and incurable neurodegenerative disease due to the loss of upper and lower motor neurons, which leads to muscle weakness, atrophy, and paralysis. Sigma‐1 receptor (σ‐1R) is a ligand‐operated protein that exhibits pro‐survival and anti‐apoptotic propert...
Autores principales: | Estévez‐Silva, Héctor M., Mediavilla, Tomás, Giacobbo, Bruno Lima, Liu, Xijia, Sultan, Fahad R., Marcellino, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305776/ https://www.ncbi.nlm.nih.gov/pubmed/35080077 http://dx.doi.org/10.1111/ejn.15608 |
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