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Inhibition of glial D‐serine release rescues synaptic damage after brain injury

Synaptic damage is one of the most prevalent pathophysiological responses to traumatic CNS injury and underlies much of the associated cognitive dysfunction; however, it is poorly understood. The D‐amino acid, D‐serine, serves as the primary co‐agonist at synaptic NMDA receptors (NDMARs) and is a cr...

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Detalles Bibliográficos
Autores principales: Tapanes, Stephen A., Arizanovska, Dena, Díaz, Madelen M., Folorunso, Oluwarotimi O., Harvey, Theresa, Brown, Stephanie E., Radzishevsky, Inna, Close, Liesl N., Jagid, Jonathan R., Graciolli Cordeiro, Joacir, Wolosker, Herman, Balu, Darrick T., Liebl, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305835/
https://www.ncbi.nlm.nih.gov/pubmed/35195906
http://dx.doi.org/10.1002/glia.24161