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Inhibition of glial D‐serine release rescues synaptic damage after brain injury
Synaptic damage is one of the most prevalent pathophysiological responses to traumatic CNS injury and underlies much of the associated cognitive dysfunction; however, it is poorly understood. The D‐amino acid, D‐serine, serves as the primary co‐agonist at synaptic NMDA receptors (NDMARs) and is a cr...
Autores principales: | Tapanes, Stephen A., Arizanovska, Dena, Díaz, Madelen M., Folorunso, Oluwarotimi O., Harvey, Theresa, Brown, Stephanie E., Radzishevsky, Inna, Close, Liesl N., Jagid, Jonathan R., Graciolli Cordeiro, Joacir, Wolosker, Herman, Balu, Darrick T., Liebl, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305835/ https://www.ncbi.nlm.nih.gov/pubmed/35195906 http://dx.doi.org/10.1002/glia.24161 |
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