Chiral Phosphoric Acid Catalyzed Conversion of Epoxides into Thiiranes: Mechanism, Stereochemical Model, and New Catalyst Design

Computations and experiments leading to new chiral phosphoric acids (CPAs) for epoxide thionations are reported. Density functional theory calculations reveal the mechanism and origin of the enantioselectivity of such CPA‐catalyzed epoxide thionations. The calculated mechanistic information was used...

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Detalles Bibliográficos
Autores principales: Duan, Meng, Díaz‐Oviedo, Christian David, Zhou, Yang, Chen, Xiangyang, Yu, Peiyuan, List, Benjamin, Houk, Kendall N., Lan, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305870/
https://www.ncbi.nlm.nih.gov/pubmed/34889494
http://dx.doi.org/10.1002/anie.202113204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305870/
https://www.ncbi.nlm.nih.gov/pubmed/34889494
http://dx.doi.org/10.1002/anie.202113204

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