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The effect of dimerization and ligand binding on the dynamics of Kaposi's sarcoma‐associated herpesvirus protease
The Kaposi's sarcoma‐associated herpesvirus protease is essential for virus maturation. This protease functions under allosteric regulation that establishes its enzymatic activity upon dimerization. It exists in equilibrium between an inactive monomeric state and an active, weakly associating,...
Autores principales: | Bern, David, Tobi, Dror |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305915/ https://www.ncbi.nlm.nih.gov/pubmed/35084062 http://dx.doi.org/10.1002/prot.26307 |
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