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Cortical and white matter lesion topology influences focal corpus callosum atrophy in multiple sclerosis

BACKGROUND AND PURPOSE: Corpus callosum (CC) atrophy is a strong predictor of multiple sclerosis (MS) disability but the contributing pathological mechanisms remain uncertain. We aimed to apply advanced MRI to explore what drives the often nonuniform callosal atrophy. METHODS: Prospective brain 7 Te...

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Detalles Bibliográficos
Autores principales: Platten, Michael, Ouellette, Russell, Herranz, Elena, Barletta, Valeria, Treaba, Constantina A., Mainero, Caterina, Granberg, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305945/
https://www.ncbi.nlm.nih.gov/pubmed/35165979
http://dx.doi.org/10.1111/jon.12977