Hobit and Blimp‐1 instruct the differentiation of iNKT cells into resident‐phenotype lymphocytes after lineage commitment

iNKT cells are CD1d‐restricted T cells that play a pro‐inflammatory or regulatory role in infectious and autoimmune diseases. Thymic precursors of iNKT cells eventually develop into distinct iNKT1, iNKT2, and iNKT17 lineages in the periphery. It remains unclear whether iNKT cells retain developmenta...

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Detalles Bibliográficos
Autores principales: Kragten, Natasja AM, Taggenbrock, Renske LRE, Parga Vidal, Loreto, van Lier, Rene AW, Stark, Regina, van Gisbergen, Klaas PJM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Innate immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305946/
https://www.ncbi.nlm.nih.gov/pubmed/34897659
http://dx.doi.org/10.1002/eji.202149360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305946/
https://www.ncbi.nlm.nih.gov/pubmed/34897659
http://dx.doi.org/10.1002/eji.202149360

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