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Mapping the Binding Sites of UDP and Prostaglandin E2 Glyceryl Ester in the Nucleotide Receptor P2Y(6)

Cyclooxygenase‐2 catalyzes the biosynthesis of prostaglandins from arachidonic acid and the biosynthesis of prostaglandin glycerol esters (PG‐Gs) from 2‐arachidonoylglycerol. PG‐Gs are mediators of several biological actions such as macrophage activation, hyperalgesia, synaptic plasticity, and intra...

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Detalles Bibliográficos
Autores principales: Zimmermann, Anne, Vu, Oanh, Brüser, Antje, Sliwoski, Gregory, Marnett, Lawrence J., Meiler, Jens, Schöneberg, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305961/
https://www.ncbi.nlm.nih.gov/pubmed/35034430
http://dx.doi.org/10.1002/cmdc.202100683