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Mapping the Binding Sites of UDP and Prostaglandin E2 Glyceryl Ester in the Nucleotide Receptor P2Y(6)
Cyclooxygenase‐2 catalyzes the biosynthesis of prostaglandins from arachidonic acid and the biosynthesis of prostaglandin glycerol esters (PG‐Gs) from 2‐arachidonoylglycerol. PG‐Gs are mediators of several biological actions such as macrophage activation, hyperalgesia, synaptic plasticity, and intra...
Autores principales: | Zimmermann, Anne, Vu, Oanh, Brüser, Antje, Sliwoski, Gregory, Marnett, Lawrence J., Meiler, Jens, Schöneberg, Torsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305961/ https://www.ncbi.nlm.nih.gov/pubmed/35034430 http://dx.doi.org/10.1002/cmdc.202100683 |
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