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Notch1 promotes ordered revascularization through Semaphorin 3g modulation of downstream vascular patterning signalling factors

ABSTRACT: Here we genetically and functionally addressed potential pathways of Notch signalling in mediating vascular regeneration in mouse models. We first used transgenic adult mice with either gain‐ or loss‐of‐function Notch signalling in vascular endothelial cells and monitored perfusion in the...

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Detalles Bibliográficos
Autores principales: Hyun, James, Lee, Monica, Rehman, Jalees, Pajcini, Kostandin V., Malik, Asrar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305962/
https://www.ncbi.nlm.nih.gov/pubmed/34921404
http://dx.doi.org/10.1113/JP282286