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MARCKSL1–2 reverses docetaxel-resistance of lung adenocarcinoma cells by recruiting SUZ12 to suppress HDAC1 and elevate miR-200b

BACKGROUND: Long non-coding RNAs (lncRNAs) are implicated in the development of multiple cancers. In our previous study, we demonstrated that HDAC1/4-mediated silencing of microRNA-200b (miR-200b) enhances docetaxel (DTX)-resistance of human lung adenocarcinoma (LAD) cells. METHODS AND RESULTS: Here...

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Detalles Bibliográficos
Autores principales: Jiang, Min, Qi, Feng, Zhang, Kai, Zhang, Xiaofei, Ma, Jingjing, Xia, Suhua, Chen, Longbang, Yu, Zhengyuan, Chen, Jing, Chen, Dongqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306054/
https://www.ncbi.nlm.nih.gov/pubmed/35864549
http://dx.doi.org/10.1186/s12943-022-01605-w