Poly(a) selection introduces bias and undue noise in direct RNA-sequencing

BACKGROUND: Genome-wide RNA-sequencing technologies are increasingly critical to a wide variety of diagnostic and research applications. RNA-seq users often first enrich for mRNA, with the most popular enrichment method being poly(A) selection. In many applications it is well-known that poly(A) sele...

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Detalles Bibliográficos
Autores principales: Viscardi, Marcus J., Arribere, Joshua A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306060/
https://www.ncbi.nlm.nih.gov/pubmed/35869428
http://dx.doi.org/10.1186/s12864-022-08762-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306060/
https://www.ncbi.nlm.nih.gov/pubmed/35869428
http://dx.doi.org/10.1186/s12864-022-08762-8

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