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The autophagy inducer trehalose stimulates macropinocytosis in NF1-deficient glioblastoma cells
BACKGROUND: Glioblastoma is a highly aggressive brain tumor. A big effort is required to find novel molecules which can cross the blood–brain barrier and efficiently kill these tumor cells. In this perspective, trehalose (α-glucopyranosyl‐[1→1]‐α‐d‐glucopyranoside), found in various dietary sources...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306097/ https://www.ncbi.nlm.nih.gov/pubmed/35864494 http://dx.doi.org/10.1186/s12935-022-02652-5 |