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The autophagy inducer trehalose stimulates macropinocytosis in NF1-deficient glioblastoma cells

BACKGROUND: Glioblastoma is a highly aggressive brain tumor. A big effort is required to find novel molecules which can cross the blood–brain barrier and efficiently kill these tumor cells. In this perspective, trehalose (α-glucopyranosyl‐[1→1]‐α‐d‐glucopyranoside), found in various dietary sources...

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Detalles Bibliográficos
Autores principales: Del Bello, Barbara, Gamberucci, Alessandra, Marcolongo, Paola, Maellaro, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306097/
https://www.ncbi.nlm.nih.gov/pubmed/35864494
http://dx.doi.org/10.1186/s12935-022-02652-5