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Interplay of Helicobacter pylori, fibroblasts, and cancer cells induces fibroblast activation and serpin E1 expression by cancer cells to promote gastric tumorigenesis

BACKGROUND: Helicobacter pylori (H. pylori) can disrupt the tight junctions between gastric epithelial cells and penetrate the intercellular spaces acting on epithelial cells, normal fibroblasts (NFs), and cancer-associated fibroblasts (CAFs), but their interaction in gastric cancer tumorigenesis an...

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Detalles Bibliográficos
Autores principales: Chen, Xueshu, Chen, Wei, Zhao, Yan, Wang, Qinrong, Wang, Wenling, Xiang, Yining, Yuan, Hang, Xie, Yuan, Zhou, Jianjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306099/
https://www.ncbi.nlm.nih.gov/pubmed/35864535
http://dx.doi.org/10.1186/s12967-022-03537-x