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Engineered exosome-mediated delivery of circDIDO1 inhibits gastric cancer progression via regulation of MiR-1307-3p/SOCS2 Axis

BACKGROUND: Our previous study has identified a novel circRNA (circDIDO1) that is down-regulated in gastric cancer (GC) and significantly inhibits GC progression. The purpose of this study is to identify the molecular mechanism for circDIDO1 and to evaluate the therapeutic effect of circDIDO1 in GC....

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Detalles Bibliográficos
Autores principales: Guo, Zhen, Zhang, Yu, Xu, Wenrong, Zhang, Xu, Jiang, Jiajia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306104/
https://www.ncbi.nlm.nih.gov/pubmed/35864511
http://dx.doi.org/10.1186/s12967-022-03527-z