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Disulfiram inhibits liver fibrosis in rats by suppressing hepatic stellate cell activation and viability

BACKGROUND: Liver fibrosis is a wound-healing response to chronic injury, featuring with excess accumulation of extracellular matrix secreted by the activated hepatic stellate cells (HSC). Disulfiram (DSF), also known as Antabuse, has been used for the treatment of alcohol addiction and substance ab...

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Detalles Bibliográficos
Autores principales: Yang, Xiao-Mei, Wu, Zheng, Wang, Xiaoqi, Zhou, Yaoqi, Zhu, Lei, Li, Dongxue, Nie, Hui-Zhen, Wang, Ya-Hui, Li, Jun, Ma, Xueyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306139/
https://www.ncbi.nlm.nih.gov/pubmed/35864505
http://dx.doi.org/10.1186/s40360-022-00583-5