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Disulfiram inhibits liver fibrosis in rats by suppressing hepatic stellate cell activation and viability
BACKGROUND: Liver fibrosis is a wound-healing response to chronic injury, featuring with excess accumulation of extracellular matrix secreted by the activated hepatic stellate cells (HSC). Disulfiram (DSF), also known as Antabuse, has been used for the treatment of alcohol addiction and substance ab...
Autores principales: | Yang, Xiao-Mei, Wu, Zheng, Wang, Xiaoqi, Zhou, Yaoqi, Zhu, Lei, Li, Dongxue, Nie, Hui-Zhen, Wang, Ya-Hui, Li, Jun, Ma, Xueyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306139/ https://www.ncbi.nlm.nih.gov/pubmed/35864505 http://dx.doi.org/10.1186/s40360-022-00583-5 |
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