Cargando…

E3 ubiquitin ligase MAGI3 degrades c-Myc and acts as a predictor for chemotherapy response in colorectal cancer

BACKGROUND: Recurrence and chemoresistance constitute the leading cause of death in colorectal cancer (CRC). Thus, it is of great significance to clarify the underlying mechanisms and identify predictors for tailoring adjuvant chemotherapy to improve the outcome of CRC. METHODS: By screening differe...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Haibo, Yang, Wenjing, Qin, Qiong, Yang, Xiaomei, Yang, Ying, Liu, Hua, Lu, Wenxiu, Gu, Siyu, Cao, Xuedi, Feng, Duiping, Zhang, Zhongtao, He, Junqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306183/
https://www.ncbi.nlm.nih.gov/pubmed/35864508
http://dx.doi.org/10.1186/s12943-022-01622-9