The mitochondrial unfolded protein response (UPR(mt)): shielding against toxicity to mitochondria in cancer

Mitochondria are essential for tumor growth and progression. However, the heavy demand for mitochondrial activity in cancer leads to increased production of mitochondrial reactive oxygen species (mtROS), accumulation of mutations in mitochondrial DNA, and development of mitochondrial dysfunction. If...

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Detalles Bibliográficos
Autores principales: Inigo, Joseph R., Chandra, Dhyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306209/
https://www.ncbi.nlm.nih.gov/pubmed/35864539
http://dx.doi.org/10.1186/s13045-022-01317-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306209/
https://www.ncbi.nlm.nih.gov/pubmed/35864539
http://dx.doi.org/10.1186/s13045-022-01317-0

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