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Syntaxin4-Munc18c Interaction Promotes Breast Tumor Invasion and Metastasis by Regulating MT1-MMP Trafficking

Invasion of neighboring extracellular matrix (ECM) by malignant tumor cells is a hallmark of metastatic progression. This invasion can be mediated by subcellular structures known as invadopodia, the function of which depends upon soluble N-ethylmaleimide-sensitive factor-activating protein receptor...

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Detalles Bibliográficos
Autores principales: Brasher, Megan I., Chafe, Shawn C., McDonald, Paul C., Nemirovsky, Oksana, Gorshtein, Genya, Gerbec, Zachary J., Brown, Wells S., Grafinger, Olivia R., Marchment, Matthew, Matus, Esther, Dedhar, Shoukat, Coppolino, Marc G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306282/
https://www.ncbi.nlm.nih.gov/pubmed/34876482
http://dx.doi.org/10.1158/1541-7786.MCR-20-0527