Brucella melitensis Wzm/Wzt System: Changes in the Bacterial Envelope Lead to Improved Rev1Δwzm Vaccine Properties

The lipopolysaccharide (LPS) O-polysaccharide (O-PS) is the main virulence factor in Brucella. After synthesis in the cytoplasmic membrane, O-PS is exported to the periplasm by the Wzm/Wzt system, where it is assembled into a LPS. This translocation also engages a bactoprenol carrier required for fu...

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Detalles Bibliográficos
Autores principales: Mena-Bueno, Sara, Poveda-Urkixo, Irati, Irazoki, Oihane, Palacios, Leyre, Cava, Felipe, Zabalza-Baranguá, Ana, Grilló, María Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306315/
https://www.ncbi.nlm.nih.gov/pubmed/35875565
http://dx.doi.org/10.3389/fmicb.2022.908495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306315/
https://www.ncbi.nlm.nih.gov/pubmed/35875565
http://dx.doi.org/10.3389/fmicb.2022.908495

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