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Designing Clinical Trials for Combination Immunotherapy: A Framework for Glioblastoma

Immunotherapy has revolutionized treatment for many hard-to-treat cancers but has yet to produce significant improvement in outcomes for patients with glioblastoma. This reflects the multiple and unique mechanisms of immune evasion and escape in this highly heterogeneous tumor. Glioblastoma engender...

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Detalles Bibliográficos
Autores principales: Singh, Kirit, Batich, Kristen A., Wen, Patrick Y., Tan, Aaron C., Bagley, Stephen J., Lim, Michael, Platten, Michael, Colman, Howard, Ashley, David M., Chang, Susan M., Rahman, Rifaquat, Galanis, Evanthia, Mansouri, Alireza, Puduvalli, Vinay K., Reardon, David A., Sahebjam, Solmaz, Sampson, John H., Simes, John, Berry, Donald A., Zadeh, Gelareh, Cloughesy, Tim F., Mehta, Minesh P., Piantadosi, Steven, Weller, Michael, Heimberger, Amy B., Khasraw, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306329/
https://www.ncbi.nlm.nih.gov/pubmed/34561270
http://dx.doi.org/10.1158/1078-0432.CCR-21-2681