Maintaining flippase activity in procoagulant platelets is a novel approach to reducing thrombin generation

BACKGROUND: During thrombosis, procoagulant platelets expose phosphatidylserine (PS), which enhances local thrombin generation. Reducing platelet PS exposure could be a novel anti‐thrombotic approach. PS is confined to the inner leaflet of the plasma membrane in unstimulated platelets by ATP‐depende...

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Detalles Bibliográficos
Autores principales: Millington‐Burgess, Sarah L., Harper, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
PLATELETS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306496/
https://www.ncbi.nlm.nih.gov/pubmed/35034417
http://dx.doi.org/10.1111/jth.15641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306496/
https://www.ncbi.nlm.nih.gov/pubmed/35034417
http://dx.doi.org/10.1111/jth.15641

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