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Maintaining flippase activity in procoagulant platelets is a novel approach to reducing thrombin generation

BACKGROUND: During thrombosis, procoagulant platelets expose phosphatidylserine (PS), which enhances local thrombin generation. Reducing platelet PS exposure could be a novel anti‐thrombotic approach. PS is confined to the inner leaflet of the plasma membrane in unstimulated platelets by ATP‐depende...

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Detalles Bibliográficos
Autores principales:	Millington‐Burgess, Sarah L., Harper, Matthew T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	PLATELETS
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306496/ https://www.ncbi.nlm.nih.gov/pubmed/35034417 http://dx.doi.org/10.1111/jth.15641

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