Impact of random variation in albuminuria and estimated glomerular filtration rate on patient enrolment and duration of clinical trials in nephrology

AIM: To test whether a screening approach with more flexible urinary albumin creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) thresholds would decrease screen failure rate without negatively impacting on the event rate and overall study duration. METHODS: We performed a post‐h...

Descripción completa

Detalles Bibliográficos
Autores principales: Waijer, Simke W., Provenzano, Michele, Mulder, Skander, Rossing, Peter, Persson, Frederik, Perkovic, Vlado, Heerspink, Hiddo J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306498/
https://www.ncbi.nlm.nih.gov/pubmed/35112455
http://dx.doi.org/10.1111/dom.14660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306498/
https://www.ncbi.nlm.nih.gov/pubmed/35112455
http://dx.doi.org/10.1111/dom.14660

Ejemplares similares