Cargando…

Impact of random variation in albuminuria and estimated glomerular filtration rate on patient enrolment and duration of clinical trials in nephrology

AIM: To test whether a screening approach with more flexible urinary albumin creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) thresholds would decrease screen failure rate without negatively impacting on the event rate and overall study duration. METHODS: We performed a post‐h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Waijer, Simke W., Provenzano, Michele, Mulder, Skander, Rossing, Peter, Persson, Frederik, Perkovic, Vlado, Heerspink, Hiddo J. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306498/ https://www.ncbi.nlm.nih.gov/pubmed/35112455 http://dx.doi.org/10.1111/dom.14660

Ejemplares similares

Short‐Term Changes in Albuminuria and Risk of Cardiovascular and Renal Outcomes in Type 2 Diabetes Mellitus: A Post Hoc Analysis of the EMPA‐REG OUTCOME Trial
por: Waijer, Simke W., et al.
Publicado: (2020)

Albuminuria and glomerular filtration rate in obese children and adolescents
por: Sawamura, Luciana Satiko, et al.
Publicado: (2018)

New clinical trial designs for establishing drug efficacy and safety in a precision medicine era
por: Heerspink, Hiddo J. L., et al.
Publicado: (2018)

Initial Angiotensin Receptor Blockade–Induced Decrease in Albuminuria Is Associated With Long-Term Renal Outcome in Type 2 Diabetic Patients With Microalbuminuria: A post hoc analysis of the IRMA-2 trial
por: Hellemons, Merel E., et al.
Publicado: (2011)

Estimation of the Cadmium Nephrotoxicity Threshold from Loss of Glomerular Filtration Rate and Albuminuria
por: Satarug, Soisungwan, et al.
Publicado: (2023)

Initiation of the SGLT2 inhibitor canagliflozin to prevent kidney and heart failure outcomes guided by HbA1c, albuminuria, and predicted risk of kidney failure
por: Tye, Sok Cin, et al.
Publicado: (2022)

Cardiovascular and renal outcomes by baseline albuminuria status and renal function: Results from the LEADER randomized trial
por: Mosenzon, Ofri, et al.
Publicado: (2020)

Changes in Albuminuria Predict Cardiovascular and Renal Outcomes in Type 2 Diabetes: A Post Hoc Analysis of the LEADER Trial
por: Persson, Frederik, et al.
Publicado: (2021)

Influence of albuminuria and glomerular filtration rate on blood pressure response to antihypertensive drug therapy
por: Flack, John M, et al.
Publicado: (2007)

Sepsis induces albuminuria and alterations in the glomerular filtration barrier: a morphofunctional study in the rat
por: Adembri, Chiara, et al.
Publicado: (2011)

Relationship between estimated glomerular filtration rate, albuminuria, and oxidant status in the Japanese population
por: Ishizaka, Yuko, et al.
Publicado: (2013)

Optimization of Albuminuria-Lowering Treatment in Diabetes by Crossover Rotation to Four Different Drug Classes: A Randomized Crossover Trial
por: Curovic, Viktor Rotbain, et al.
Publicado: (2023)

Monitoring Kidney Function and Albuminuria in Patients With Diabetes
por: Lambers Heerspink, Hiddo J., et al.
Publicado: (2011)

Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx
por: Crompton, Michael, et al.
Publicado: (2023)

Albuminuria and the Duration of Albuminuria in Cholera
por: Brahmachari, U. N.
Publicado: (1907)

How to measure and monitor albuminuria in healthy toddlers?
por: van den Belt, Sophie Marielle, et al.
Publicado: (2018)

The Impact of Sotagliflozin on Renal Function, Albuminuria, Blood Pressure, and Hematocrit in Adults With Type 1 Diabetes
por: van Raalte, Daniël H., et al.
Publicado: (2019)

Change in the Distribution of Albuminuria According to Estimated Glomerular Filtration Rate in Pima Indians With Type 2 Diabetes
por: Pavkov, Meda E., et al.
Publicado: (2009)

Arterial Stiffness Is Associated With Incident Albuminuria and Decreased Glomerular Filtration Rate in Type 2 Diabetic Patients
por: Bouchi, Ryotaro, et al.
Publicado: (2011)

Associations of estimated glomerular filtration rate and albuminuria with mortality and renal failure by sex: a meta-analysis
por: Nitsch, Dorothea, et al.
Publicado: (2013)

The association of chronic kidney disease complications by albuminuria and glomerular filtration rate: a cross-sectional analysis
por: Viswanathan, Gautham, et al.
Publicado: (2013)

Inflammation, oxidative stress, glomerular filtration rate, and albuminuria in elderly men: a cross-sectional study
por: Nerpin, Elisabet, et al.
Publicado: (2012)

Burden of Chronic Kidney Disease by KDIGO Categories of Glomerular Filtration Rate and Albuminuria: A Systematic Review
por: Murton, Molly, et al.
Publicado: (2020)

Reduction in albuminuria with dapagliflozin cannot be predicted by baseline clinical characteristics or changes in most other risk markers
por: Heerspink, Hiddo J. L., et al.
Publicado: (2018)

Longitudinal relationship between albuminuria in infancy and childhood
por: Gracchi, Valentina, et al.
Publicado: (2023)

Genetic Modifiers of White Blood Cell Count, Albuminuria and Glomerular Filtration Rate in Children with Sickle Cell Anemia
por: Schaefer, Beverly A., et al.
Publicado: (2016)

Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease
por: Lees, Jennifer S, et al.
Publicado: (2019)

Dietary Acid Load and Relationship with Albuminuria and Glomerular Filtration Rate in Individuals with Chronic Kidney Disease at Predialysis State
por: Silva, Luísa, et al.
Publicado: (2021)

Discrepancies in estimated glomerular filtration rate and albuminuria levels in ethnic minority groups – The multiethnic HELIUS cohort study
por: Huisman, Brechje J.M.V., et al.
Publicado: (2022)

Plasma galectin-3 concentration and estimated glomerular filtration rate in patients with type 2 diabetes with and without albuminuria
por: Chung, Jin Ook, et al.
Publicado: (2022)

Glomerular filtration rate and albuminuria predict mortality independently from coronary artery calcified plaque in the Diabetes Heart Study
por: Cox, Amanda J, et al.
Publicado: (2013)

Albuminuria and neck circumference are determinate factors of successful accurate estimation of glomerular filtration rate in high cardiovascular risk patients
por: Hsiao, Po-Jen, et al.
Publicado: (2018)

GlycA, a marker of protein glycosylation, is related to albuminuria and estimated glomerular filtration rate: the ELSA-Brasil study
por: Titan, Silvia M., et al.
Publicado: (2017)

Development and Validation of a Prediction Model for Future Estimated Glomerular Filtration Rate in People With Type 2 Diabetes and Chronic Kidney Disease
por: Gregorich, Mariella, et al.
Publicado: (2023)

Retinol-binding protein 4 versus albuminuria as predictors of estimated glomerular filtration rate decline in patients with type 2 diabetes
por: Klisic, Aleksandra, et al.
Publicado: (2018)

Impaired glomerular filtration rate, high grade albuminuria and associated factors among adult patients admitted to tertiary Hospital in Ethiopia
por: Adugna, Tamiru, et al.
Publicado: (2018)

Value of Estimated Glomerular Filtration Rate and Albuminuria in Predicting Cardiovascular Risk in Patients with Type 2 Diabetes without Cardiovascular Disease
por: Weerarathna, Thilak, et al.
Publicado: (2018)

OR28-3 Ethnic Differences in Albuminuria among Adults with Diabetes and Normal Range Estimated Glomerular Filtration Rate (eGFR).
por: Arzumanyan, Hasmik, et al.
Publicado: (2022)

YKL-40, a Marker of Inflammation and Endothelial Dysfunction, Is Elevated in Patients With Type 1 Diabetes and Increases With Levels of Albuminuria
por: Rathcke, Camilla Noelle, et al.
Publicado: (2009)

Determining the optimal dose of atrasentan by evaluating the exposure‐response relationships of albuminuria and bodyweight
por: Koomen, Jeroen V., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_28oppclunvt61dd3c4t4gsndqo