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Acute response to cholinergic challenge predicts long‐term response to galantamine treatment in patients with Alzheimer's disease

AIMS: Cholinesterase inhibitors (CEIs) have been shown to improve cognitive functioning in Alzheimer's disease (AD) patients, but are associated with multiple side effects and only 20–40% of the patients clinically improve. In this study, we aimed to investigate the acute pharmacodynamic (PD) e...

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Detalles Bibliográficos
Autores principales: Baakman, Anne Catrien, Gavan, Carmen, van Doeselaar, Lotte, de Kam, Marieke, Broekhuizen, Karen, Bajenaru, Ovidiu, Camps, Laura, Swart, Eleonora L., Kalisvaart, Kees, Schoonenboom, Niki, Lemstra, Evelien, Scheltens, Philip, Cohen, Adam, van Gerven, Joop, Groeneveld, Geert Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306507/
https://www.ncbi.nlm.nih.gov/pubmed/34964149
http://dx.doi.org/10.1111/bcp.15206