Cargando…

Direct Addition of Grignard Reagents to Aliphatic Carboxylic Acids Enabled by Bulky turbo‐Organomagnesium Anilides

The synthesis of ketones through addition of organometallic reagents to aliphatic carboxylic acids is a straightforward strategy that is limited to organolithium reagents. More desirable Grignard reagents can be activated and controlled with a bulky aniline‐derived turbo‐Hauser base. This operationa...

Descripción completa

Detalles Bibliográficos
Autores principales: Colas, Kilian, V. D. dos Santos, A. Catarina, Kohlhepp, Stefanie V., Mendoza, Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306512/
https://www.ncbi.nlm.nih.gov/pubmed/35084063
http://dx.doi.org/10.1002/chem.202104053