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Direct Addition of Grignard Reagents to Aliphatic Carboxylic Acids Enabled by Bulky turbo‐Organomagnesium Anilides
The synthesis of ketones through addition of organometallic reagents to aliphatic carboxylic acids is a straightforward strategy that is limited to organolithium reagents. More desirable Grignard reagents can be activated and controlled with a bulky aniline‐derived turbo‐Hauser base. This operationa...
Autores principales: | Colas, Kilian, V. D. dos Santos, A. Catarina, Kohlhepp, Stefanie V., Mendoza, Abraham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306512/ https://www.ncbi.nlm.nih.gov/pubmed/35084063 http://dx.doi.org/10.1002/chem.202104053 |
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