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Enantiocomplementary Michael Additions of Acetaldehyde to Aliphatic Nitroalkenes Catalyzed by Proline‐Based Carboligases

The blockbuster drug Pregabalin is widely prescribed for the treatment of painful diabetic neuropathy. Given the continuous epidemic growth of diabetes, the development of sustainable synthesis routes for Pregabalin and structurally related pharmaceutically active γ‐aminobutyric acid (GABA) derivati...

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Detalles Bibliográficos
Autores principales: Kunzendorf, Andreas, Saifuddin, Mohammad, Poelarends, Gerrit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306545/
https://www.ncbi.nlm.nih.gov/pubmed/35049100
http://dx.doi.org/10.1002/cbic.202100644