Selective Para‐C−H Alkynylation of Aniline Derivatives by Pd/S,O‐Ligand Catalysis

Herein, we report a nondirected para‐selective C−H alkynylation of aniline derivatives by a Pd/S,O‐ligand‐based catalyst. The reaction proceeds under mild conditions and is compatible with a variety of substituted anilines. The scalability and further derivatizations of the alkynylated products have...

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Autores principales: Deng, Ke‐Zuan, Jia, Wen‐Liang, Ángeles Fernández‐Ibáñez, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306564/
https://www.ncbi.nlm.nih.gov/pubmed/34902180
http://dx.doi.org/10.1002/chem.202104107
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author Deng, Ke‐Zuan
Jia, Wen‐Liang
Ángeles Fernández‐Ibáñez, M.
author_facet Deng, Ke‐Zuan
Jia, Wen‐Liang
Ángeles Fernández‐Ibáñez, M.
author_sort Deng, Ke‐Zuan
collection PubMed
description Herein, we report a nondirected para‐selective C−H alkynylation of aniline derivatives by a Pd/S,O‐ligand‐based catalyst. The reaction proceeds under mild conditions and is compatible with a variety of substituted anilines. The scalability and further derivatizations of the alkynylated products have been also demonstrated.
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spelling pubmed-93065642022-07-28 Selective Para‐C−H Alkynylation of Aniline Derivatives by Pd/S,O‐Ligand Catalysis Deng, Ke‐Zuan Jia, Wen‐Liang Ángeles Fernández‐Ibáñez, M. Chemistry Research Articles Herein, we report a nondirected para‐selective C−H alkynylation of aniline derivatives by a Pd/S,O‐ligand‐based catalyst. The reaction proceeds under mild conditions and is compatible with a variety of substituted anilines. The scalability and further derivatizations of the alkynylated products have been also demonstrated. John Wiley and Sons Inc. 2022-01-12 2022-02-16 /pmc/articles/PMC9306564/ /pubmed/34902180 http://dx.doi.org/10.1002/chem.202104107 Text en © 2022 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Deng, Ke‐Zuan
Jia, Wen‐Liang
Ángeles Fernández‐Ibáñez, M.
Selective Para‐C−H Alkynylation of Aniline Derivatives by Pd/S,O‐Ligand Catalysis
title Selective Para‐C−H Alkynylation of Aniline Derivatives by Pd/S,O‐Ligand Catalysis
title_full Selective Para‐C−H Alkynylation of Aniline Derivatives by Pd/S,O‐Ligand Catalysis
title_fullStr Selective Para‐C−H Alkynylation of Aniline Derivatives by Pd/S,O‐Ligand Catalysis
title_full_unstemmed Selective Para‐C−H Alkynylation of Aniline Derivatives by Pd/S,O‐Ligand Catalysis
title_short Selective Para‐C−H Alkynylation of Aniline Derivatives by Pd/S,O‐Ligand Catalysis
title_sort selective para‐c−h alkynylation of aniline derivatives by pd/s,o‐ligand catalysis
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306564/
https://www.ncbi.nlm.nih.gov/pubmed/34902180
http://dx.doi.org/10.1002/chem.202104107
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