Amyloid‐β plaques affect astrocyte Kir4.1 protein expression but not function in the dentate gyrus of APP/PS1 mice

Alzheimer pathology is accompanied by astrogliosis. Reactive astrocytes surrounding amyloid plaques may directly affect neuronal communication, and one of the mechanisms by which astrocytes impact neuronal function is by affecting K(+) homeostasis. Here we studied, using hippocampal slices from 9‐mo...

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Detalles Bibliográficos
Autores principales: Huffels, Christiaan F. M., Osborn, Lana M., Hulshof, Lianne A., Kooijman, Lieneke, Henning, Lukas, Steinhäuser, Christian, Hol, Elly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306581/
https://www.ncbi.nlm.nih.gov/pubmed/34981861
http://dx.doi.org/10.1002/glia.24137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306581/
https://www.ncbi.nlm.nih.gov/pubmed/34981861
http://dx.doi.org/10.1002/glia.24137

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