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Amyloid‐β plaques affect astrocyte Kir4.1 protein expression but not function in the dentate gyrus of APP/PS1 mice
Alzheimer pathology is accompanied by astrogliosis. Reactive astrocytes surrounding amyloid plaques may directly affect neuronal communication, and one of the mechanisms by which astrocytes impact neuronal function is by affecting K(+) homeostasis. Here we studied, using hippocampal slices from 9‐mo...
Autores principales: | Huffels, Christiaan F. M., Osborn, Lana M., Hulshof, Lianne A., Kooijman, Lieneke, Henning, Lukas, Steinhäuser, Christian, Hol, Elly M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306581/ https://www.ncbi.nlm.nih.gov/pubmed/34981861 http://dx.doi.org/10.1002/glia.24137 |
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