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Baseline type 2 biomarker levels and response to tezepelumab in severe asthma

BACKGROUND: Tezepelumab is a human monoclonal antibody that blocks activity of thymic stromal lymphopoietin (TSLP). In the phase IIb PATHWAY study (NCT02054130), tezepelumab significantly reduced annualized asthma exacerbation rates (AAERs) versus placebo in adults with severe, uncontrolled asthma....

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Detalles Bibliográficos
Autores principales: Corren, Jonathan, Pham, Tuyet‐Hang, Garcia Gil, Esther, Sałapa, Kinga, Ren, Pin, Parnes, Jane R., Colice, Gene, Griffiths, Janet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306691/
https://www.ncbi.nlm.nih.gov/pubmed/34913186
http://dx.doi.org/10.1111/all.15197