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Evaluation of sex differences in the pharmacokinetics of oral sumatriptan in healthy Korean subjects using population pharmacokinetic modeling

Sumatriptan was introduced in 1983, as the first of the triptans, selective 5‐hydroxytryptamine (5‐HT(1B/1D)) receptor agonists, to treat moderate to severe migraine. Migraine predominates in females. Although there have been reports of sex differences in migraine‐associated features and pharmacokin...

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Detalles Bibliográficos
Autores principales: Ohk, Boram, Seong, Sookjin, Lee, Joomi, Gwon, Miri, Kang, Wooyoul, Lee, Haewon, Yoon, Youngran, Yoo, Heedoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306698/
https://www.ncbi.nlm.nih.gov/pubmed/34923646
http://dx.doi.org/10.1002/bdd.2307